Systems and methods for providing proximity awareness to pleural boundaries, vascular structures, and other critical intra-thoracic structures during electromagnetic navigation bronchoscopy

ABSTRACT

Disclosed are systems, devices and methods for providing proximity awareness to an anatomical feature while navigating inside a patient&#39;s chest, an exemplary method including receiving image data of the patient&#39;s chest, generating a three-dimensional (3D) model of the patient&#39;s chest based on the received image data, determining a location of the anatomical feature based on the received image data and the generated 3D model, tracking a position of an electromagnetic sensor included in a tool, iteratively determining a position of the tool inside the patient&#39;s chest based on the tracked position of the electromagnetic sensor, and indicating a proximity of the tool relative to the anatomical feature, based on the determined position of the tool inside the patient&#39;s chest.

CROSS-REFERENCE TO RELATED APPLICATIONS

This application is a continuation of U.S. patent application Ser. No.15/254,100, filed on Sep. 1, 2016, the entire contents of which beingincorporated by reference herein.

FIELD

The present disclosure relates to navigation of surgical tools within apatient's chest, and more specifically, to systems and methods forproviding proximity awareness to pleural boundaries of the patient'slungs and vascular structures while navigating the patient's chest.

BACKGROUND

Early stage diagnosis is one of many important facets in the battleagainst lung cancer. The National Lung Screening Trial has demonstratedthat a reduction in mortality occurs if diagnostic scans, such ascomputed tomography (CT) scans, are used for early detection for thoseat risk of contracting the disease. While CT scans increase thepossibility that small lesions and nodules in the lung can be detected,these lesions and nodules still require biopsy and cytologicalexamination before a diagnosis can be rendered and treatment can beundertaken.

To perform a biopsy, as well as with many other treatments, navigationof tools within the lungs to a target location, such as the point ofbiopsy or treatment, is necessary. For example, bronchoscopy is amedical procedure used to diagnose and treat various lung diseases bynavigating one or more tools into the airways of the patient's lungs.The pleura, or pleural surfaces, form the outer boundaries of thepatient's lungs and are composed of two serous membranes: the outerparietal pleura line the inner wall of the rib cage, and the innervisceral pleura directly line the surface of the lungs. Injuries, suchas pneumothorax and pneumomediastinum may be attributed to a toolpuncturing, injuring, or violating the visceral pleural surface. Thisdanger, therefore, would also apply to any vascular or other criticalintra-thoracic structure that might be injured that are in the area orinterposed between the tools and the target or area of interest. Thus,to reduce the potential for injury, improvements to systems and methodsof navigating are continually being sought.

SUMMARY

Provided in accordance with the present disclosure is a method forproviding proximity awareness to an anatomical feature while navigatinginside a patient's chest. In an aspect of the present disclosure, themethod includes receiving image data of the patient's chest, generatinga three-dimensional (3D) model of the patient's chest based on thereceived image data, determining a location of the anatomical featurebased on the received image data and the generated 3D model, tracking aposition of an electromagnetic sensor included in a tool, iterativelydetermining a position of the tool inside the patient's chest based onthe tracked position of the electromagnetic sensor, and indicating aproximity of the tool relative to the anatomical feature, based on thedetermined position of the tool inside the patient's chest.

In another aspect of the present disclosure, the method further includesdetermining whether the tool is within a predetermined distance from theanatomical feature, and providing a proximity alert, in response to adetermination that the tool is within the predetermined distance fromthe anatomical feature.

In a further aspect of the present disclosure, the method furtherincludes receiving data corresponding to movement of the patient's chestbased on the patient's respiratory cycle, and wherein determiningwhether the tool is within the predetermined distance from theanatomical feature includes determining whether the tool is within thepredetermined distance from the anatomical feature based on the dataregarding movement of the patient's chest.

In another aspect of the present disclosure, the method further includesreceiving data corresponding to movement of the patient's chest based onthe patient's respiratory cycle, and wherein determining the location ofthe anatomical feature includes determining the location of theanatomical feature based on the data corresponding to the movement ofthe patient's chest.

In a further aspect of the present disclosure, the anatomical feature isa pleural surface of the patient's lungs.

In another aspect of the present disclosure, the anatomical feature is avascular structure.

In a further aspect of the present disclosure, the method furtherincludes receiving additional image data of the patient's chest, andupdating the 3D model based on the additional image data.

In another aspect of the present disclosure, the indicating theproximity of the tool relative to the anatomical feature includesdisplaying a distance between the tool and the anatomical feature, and adirection of the tool relative to the anatomical feature.

Provided in accordance with the present disclosure is a system forproviding proximity awareness to an anatomical feature while navigatinginside a patient's chest. In an aspect of the present disclosure, thesystem includes an electromagnetic navigation system including anelectromagnetic field generator, a tool configured to be inserted intothe patient's chest, and an electromagnetic sensor disposed on the tool,and a computing device including a processor and a memory storinginstructions which, when executed by the processor, cause the computingdevice to receive image data of the patient's chest, generate athree-dimensional (3D) model of the patient's chest based on thereceived image data, determine a location of the anatomical featurebased on the received image data and the generated 3D model, track aposition of the electromagnetic sensor, iteratively determine a positionof the tool inside the patient's chest based on the tracked position ofthe electromagnetic sensor, and provide instructions to indicate aproximity of the tool relative to the anatomical feature, based on thedetermined position of the tool inside the patient's chest.

In another aspect of the present disclosure, the instructions furthercause the computing device to determine whether the tool is within apredetermined distance from the anatomical feature, and provide aproximity alert when a determination is made that the tool is within thepredetermined distance from the anatomical feature.

In a further aspect of the present disclosure, the instructions furthercause the computing device to receive data corresponding to movement ofthe patient's chest based on the patient's respiratory cycle, andwherein the computing device determines whether the tool is within thepredetermined distance from the anatomical feature by determiningwhether the tool is within the predetermined distance from theanatomical feature based on the data regarding movement of the patient'schest.

In another aspect of the present disclosure, the instructions furthercause the computing device to receive data corresponding to movement ofthe patient's chest based on the patient's respiratory cycle, andwherein the computing device determines the location of the anatomicalfeature by determining the location of the anatomical feature based onthe data corresponding to the movement of the patient's chest.

In a further aspect of the present disclosure, the anatomical feature isa pleural surface of the patient's lungs.

In another aspect of the present disclosure, the anatomical feature is avascular structure.

In a further aspect of the present disclosure, the instructions furthercause the computing device to receive additional image data of thepatient's chest, and update the 3D model based on the additional imagedata.

In another aspect of the present disclosure, the indication of theproximity of the tool relative to the anatomical feature includes adistance between the tool and the anatomical feature, and a direction ofthe tool relative to the anatomical feature.

Provided in accordance with the present disclosure is a non-transitorycomputer-readable storage medium storing instructions for providingproximity awareness to an anatomical feature while navigating inside apatient's chest. In an aspect of the present disclosure, theinstructions, when executed by a processor, cause a computer to receiveimage data of the patient's chest, generate a three-dimensional (3D)model of the patient's chest based on the received image data, determinea location of the anatomical feature based on the received image dataand the generated 3D model, track a position of the electromagneticsensor, iteratively determine a position of the tool inside thepatient's chest based on the tracked position of the electromagneticsensor, and provide instructions indicate a proximity of the toolrelative to the anatomical feature, based on the determined position ofthe tool inside the patient's chest.

In another aspect of the present disclosure, the instructions furthercause the computer to determine whether the tool is within apredetermined distance from the anatomical feature, and provide aproximity alert when a determination is made that the tool is within thepredetermined distance from the anatomical feature.

In a further aspect of the present disclosure, the instructions furthercause the computer to receive additional image data of the patient'schest, and update the 3D model based on the additional image data.

In another aspect of the present disclosure, the indication of theproximity of the tool relative to the anatomical feature includes adistance between the tool and the anatomical feature, and a direction ofthe tool relative to the anatomical feature.

Any of the above aspects and embodiments of the present disclosure maybe combined without departing from the scope of the present disclosure.

BRIEF DESCRIPTION OF THE DRAWINGS

Various aspects and features of the present disclosure are describedhereinbelow with references to the drawings, wherein:

FIG. 1 is a system diagram of an electromagnetic navigation (EMN)system, which may be used to provide proximity awareness to pleuralboundaries and vascular structures, according to an embodiment of thepresent disclosure;

FIG. 2 is a schematic diagram of a computing device forming part of theEMN system of FIG. 1 , which may be used to provide proximity awarenessto pleural boundaries and vascular structures, according to anembodiment of the present disclosure;

FIGS. 3A-3C is a flowchart illustrating a method for providing proximityawareness to pleural boundaries and vascular structures, according to anembodiment of the present disclosure;

FIG. 4 is an exemplary view of a graphical user interface (GUI) forproviding proximity awareness to critical structures that may bedisplayed by a computing device forming part of the EMN system of FIG. 1;

FIG. 5 is a schematic diagram of a percutaneous surgical planning andprocedure system, according to an embodiment of the present disclosure;and

FIG. 6 is an exemplary view of a GUI for providing proximity awarenessto critical structures that may be displayed by a computing deviceforming part of the microwave ablation system of FIG. 5 .

DETAILED DESCRIPTION

Methods, systems, and computer-readable media for providing proximityawareness to intra-thoracic structures, pleural boundaries, and vascularstructures during tool navigation inside a patient's chest are providedin accordance with the present disclosure.

The methods, systems, and computer-readable media described herein areuseful in various planning and/or navigation contexts for proceduresperformed on the patient's chest. For example, in an embodiment in whicha clinician is performing a bronchoscopy, the methods and systems mayalert the clinician as to the proximity of the tools relative to thepatient's pleural surfaces. Additionally, as will be described infurther detail below, in configurations of the system in which alocation sensor is incorporated into a tool and/or catheters to trackthe location and assist in navigation of the tools, the tracked locationof the location sensor may be used to visually show the location of thetools on a three-dimensional (3D) model of the patient's chest and theproximity of the tools relative to the target location. Moreover, byproviding the location of the location sensor within the body of apatient with reference to the 3D model and/or two-dimensional (2D)images along with a planned pathway, the clinician may be able tonavigate about the lungs of the patient with improved proximityawareness to such pleural boundaries and vascular structures to therebypermit the clinician to exercise additional caution during a procedure.These and other aspects of the present disclosure are detailed hereinbelow.

Methods for proximity awareness to pleural boundaries and vascularstructures may be implemented via an electromagnetic navigation (EMN)system. Generally, in an embodiment, the EMN system may be used inplanning a pathway the target location, navigating a positioningassembly to the target location, and navigating a variety of tools, suchas a locatable guide (LG) and/or a treatment tool, such as a biopsy toolor an ablation tool, to the target location. The EMN system may beconfigured to display various views of the patient's body, and of theaforementioned 3D model.

With reference to FIG. 1 , an endobronchial EMN system 10 suitable forimplementing methods for proximity awareness to pleural boundaries andvascular structures is provided in accordance with the presentdisclosure. One such EMN system 10 is the ELECTROMAGNETIC NAVIGATIONBRONCHOSCOPY® system currently sold by Covidien LP. As shown in FIG. 1 ,EMN system 10 is used to perform one or more procedures on a patientsupported on an operating table 40. In this regard, EMN system 10generally includes a bronchoscope 50, monitoring equipment 60, anelectromagnetic (EM) tracking system 70, and a computing device 80.

Bronchoscope 50 is configured for insertion through the patient's mouthand/or nose into the patient's airways. As illustrated in FIG. 1 , thepatient is shown lying on operating table 40 with bronchoscope 50inserted through the patient's mouth and into the patient's airways.Bronchoscope 50 includes a source of illumination and a video imagingsystem (not explicitly shown) and is coupled to monitoring equipment 60,for example, a video display, for displaying the video images receivedfrom the video imaging system of bronchoscope 50.

In an embodiment, bronchoscope 50 may operate in conjunction with acatheter guide assembly, two types of which are depicted in FIG. 1 (forexample, catheter guide assemblies 90, 100). Catheter guide assemblies90, 100 including LG 92 and EWC 96 are configured for insertion througha working channel of bronchoscope 50 into the patient's airways(although the catheter guide assemblies 90, 100 may alternatively beused without bronchoscope 50). Although configured differently, catheterguide assemblies 90, 100 share a number of common components.Specifically each catheter guide assembly 90, 100 includes a handle 91,which is connected to an extended working channel (EWC) 96. In eachassembly 90, 100, EWC 96 is sized for placement into the working channelof bronchoscope 50. In the operation of each assembly 90, 100, alocatable guide (LG) 92, including an EM sensor 94, is inserted into EWC96 and locked into position such that EM sensor 94 extends a desireddistance beyond the distal tip 93 of EWC 96. The location of EM sensor94, and thus the distal end of EWC 96, within an EM field generated byEM field generator 76 can be derived by tracking module 72, andcomputing device 80. Catheter guide assemblies 90, 100 may havedifferent operating mechanisms, but each includes handle 91 that can bemanipulated by rotation and compression to steer distal tip 93 of LG 92and EWC 96.

Catheter guide assembly 90 is currently marketed and sold by Covidien LPunder the name SUPERDIMENSION® Procedure Kits. Catheter guide assembly100 is currently sold by Covidien LP under the name EDGE™ ProcedureKits. Both kits include handle 91, EWC 96, and LG 92. For a moredetailed description of catheter guide assemblies 90, 100, reference ismade to commonly-owned U.S. Pat. No. 9,247,992, entitled “MICROWAVEABLATION CATHETER AND METHOD OF UTILIZING THE SAME”, filed on Mar. 15,2013 by Ladtkow et al., the entire contents of which are herebyincorporated by reference.

LG 92 and EWC 96 are selectively lockable relative to one another via alocking mechanism 99. A six degrees-of-freedom EM tracking system 70,e.g., similar to those disclosed in U.S. Pat. No. 6,188,355 andpublished PCT Application Nos. WO 00/10456 and WO 01/67035, entitled“WIRELESS SIX-DEGREE-OF-FREEDOM LOCATOR”, filed on Dec. 14, 1998 byGilboa, the entire contents of each of which is incorporated herein byreference, or any other suitable positioning measuring system, isutilized for performing navigation, although other configurations arealso contemplated.

EM tracking system 70 may be configured for use with catheter guideassemblies 90, 100 to track the position of EM sensor 94 as it moves inconjunction with EWC 96 through the airways of the patient, as detailedbelow. In an embodiment, EM tracking system 70 includes a trackingmodule 72, a plurality of reference sensors 74, and an EM fieldgenerator 76. As shown in FIG. 1 , EM field generator 76 is positionedbeneath the patient. EM field generator 76 and the plurality ofreference sensors 74 are interconnected with tracking module 72, whichderives the location of each reference sensor 74 in the six degrees offreedom. One or more of reference sensors 74 are attached to the chestof the patient. The six degrees of freedom coordinates of referencesensors 74 are sent as data to computing device 80, which includesapplication 81, where the data from sensors 74 are used to calculate apatient coordinate frame of reference.

Although EM sensor 94 is described above as being included in LG 92 itis also envisioned that EM sensor 94 may be embedded or incorporatedwithin a biopsy tool 102 where biopsy tool 102 may alternatively beutilized for navigation without need of LG 92 or the necessary toolexchanges that use of LG 92 requires. Similarly, it is envisioned thatEM sensor 94 may be embedded or incorporated within a microwave ablationtool 104, where microwave ablation tool 104 may alternatively beutilized for navigation without the need of LG 92 or the necessary toolexchanges that use of LG 92 requires.

According to an embodiment, biopsy tool 102 is configured to beinsertable into catheter guide assemblies 90, 100 following navigationto a target location and removal of LG 92. Biopsy tool 102 may be usedto collect one or more tissue samples from the target location, and inan embodiment, is further configured for use in conjunction withtracking system 70 to facilitate navigation of biopsy tool 102 to thetarget location, and tracking of a location of biopsy tool 102 as it ismanipulated relative to the target location to obtain the tissue sample.Similarly, microwave ablation tool 104 is configured to be insertableinto catheter guide assemblies 90, 100 following navigation to a targetlocation and removal of LG 92. Microwave ablation tool 104 is configuredto be operated with a microwave generator 106, and may include any of avariety of microwave ablation tools and/or catheters, examples of whichare more fully described in U.S. Pat. Nos. 9,259,269; 9,247,993;9,044,254; 9,370,398; and 9,993,295, the entire contents of each ofwhich is incorporated herein by reference. Though shown as a biopsy tooland microwave ablation tool in FIG. 1 , those of skill in the art willrecognize that other tools including for example RF ablation tools,brachytherapy tools, and others may be similarly deployed and trackedwithout departing from the scope of the present disclosure.

For example, a variety of useable biopsy tools are described in U.S.Patent Publication No. 2015/0141809, entitled “DEVICES, SYSTEMS, ANDMETHODS FOR NAVIGATING A BIOPSY TOOL TO A TARGET LOCATION AND OBTAININGA TISSUE SAMPLE USING THE SAME”, filed Sep. 17, 2014, by Costello etal., and U.S. Pat. No. 10,278,680, entitled “DEVICES, SYSTEMS, ANDMETHODS FOR NAVIGATING A BIOPSY TOOL TO A TARGET LOCATION AND OBTAININGA TISSUE SAMPLE USING THE SAME”, filed Dec. 9, 2014, by Costello et al.,the contents of each of which are incorporated herein by reference anduseable with the EMN system 10 as described herein.

Computing device 80 includes software and/or hardware, such as an EMNapplication 81, used to facilitate the various phases of an EMNprocedure, including generating the 3D model, identification of a targetlocation, planning a pathway to the target location, registration of the3D model with the patient's actual airways, and navigation to the targetlocation. For example, during procedure planning, computing device 80utilizes computed tomographic (CT) scan, magnetic resonance imaging (MM)scan, X-ray scan, cone beam computed tomography (CBCT) scan, and/orpositron emission tomography (PET) scan image data for generating andviewing the 3D model of the patient's airways, enables theidentification of a target location on the 3D model (automatically,semi-automatically or manually), and allows for the determination andselection of a pathway through the patient's airways to the targetlocation. While the CT scan image data may have gaps, omissions, and/orother imperfections included in the image data, the 3D model is a smoothrepresentation of the patient's airways, with any such gaps, omissions,and/or imperfections in the CT scan image data filled in or corrected.The 3D model may be presented on a display monitor associated withcomputing device 80, or in any other suitable fashion. An example of theplanning software described herein can be found in U.S. Pat. Nos.9,459,770, 9,925,009, and 9,639,666, filed by Baker et al. on Mar. 15,2013, and entitled “PATHWAY PLANNING SYSTEM AND METHOD”, the contents ofall of which are incorporated herein by reference. Further examples ofthe planning software can be found in commonly assigned U.S. Pat. No.9,770,216, entitled “SYSTEM AND METHOD FOR NAVIGATING WITHIN THE LUNG”,filed on Jun. 29, 2015, by Brown et al., the contents of which areincorporated herein by reference.

Using computing device 80, various views of the 3D model may bepresented and may be manipulated by a clinician to facilitateidentification of a target location and selection of a suitable pathwaythrough the patient's airways to access the target location. The 3Dmodel may include, among other things, a model airway tree correspondingto the actual airways of the patient's lungs, and showing the variouspassages, branches, and bifurcations of the patient's actual airwaytree. Additionally, the 3D model may include lesions, markers, bloodvessels and vascular structures, lymphatic vessels and structures,organs, other physiological structures, and/or a 3D rendering of thepleura. Some or all of the aforementioned elements may be selectivelydisplayed, such that the clinician may choose which elements should bedisplayed during when viewing the 3D model. For example, EMN application81 may be configured in various states to display the 3D model in avariety of view modes. For each view of the 3D model, the angle fromwhich the 3D model is displayed may correspond to a view point. The viewpoint may be fixed at a predefined location and/or orientation, or maybe adjusted by the clinician operating computing device 80.

Following pathway planning, a procedure may be undertaken in which EMsensor 94, in conjunction with tracking system 70, enables tracking ofEM sensor 94 (and thus the distal end of EWC 96 or tool 102) as EMsensor 94 is advanced through the patient's airways following thepathway planned during the pathway planning phase. As an initial step ofthe procedure, the 3D model is registered with the patient's actualairways. One potential method of registration involves navigating alocatable guide into each lobe of the patient's lungs to at least thesecond bifurcation of the airways of that lobe. The position of thelocatable guide is tracked during this registration phase, and the 3Dmodel is iteratively updated based on the tracked position of thelocatable guide within the actual airways of the patient's lungs. Thisregistration process is described in commonly-owned U.S. PatentApplication Publication No. 2011/0085720, entitled “AUTOMATICREGISTRATION TECHNIQUE,” filed on May 14, 2010, by Barak et al., andU.S. Pat. No. 10,772,532, entitled “REAL-TIME AUTOMATIC REGISTRATIONFEEDBACK”, filed on Jul. 2, 2015, by Brown et al., the contents of eachof which are incorporated herein by reference. While the registrationprocess focuses on aligning the patient's actual airways with theairways of the 3D model, registration also ensures that the position ofvascular structures and the pleura are accurately determined.

Turning now to FIG. 2 , computing device 80 may include a memory 202, aprocessor 204, a display 206, a network interface 208, an input device210, and/or an output module 212. Memory 202 may store application 81and/or image data 214. Application 81 may, when executed by processor204, cause display 206 to present user interface 216. Application 81 mayalso provide the interface between the sensed position of EM sensor 94and the image and planning data developed in the pathway planning phase.

Referring now to FIGS. 3A-3C, an exemplary computer-implemented method300 is provided for providing proximity awareness to pleural boundariesand vascular structures. Method 300 may be implemented, at least inpart, by processor 204 executing application 81 stored in memory 202.Additionally, the particular sequence of steps shown in the method 300of FIGS. 3A-3C is provided by way of example and not limitation. Thus,the steps of the method 300 may be executed in sequences other than thesequence shown in FIGS. 3A-3C without departing from the scope of thepresent disclosure. Further, some steps shown in the method 300 of FIGS.3A-3C may be concurrently executed with respect to one another insteadof sequentially executed with respect to one another. Method 300 may beimplemented using a variety of different tools, systems, and surgicalapproaches. For example, method 300 may be implemented using anendobronchial navigation system, such as EMN system 10 of FIG. 1(described above). Alternatively, method 300 may be implemented using apercutaneous surgical system, such as system 500 of FIG. 5 (describedbelow).

In an embodiment, method 300 generally includes a planning phase, shownin FIG. 3A, followed by a navigation phase, shown in FIGS. 3B and 3C.The planning phase of method 300 may begin at step S302, where computingdevice 80 receives image data of the patient's chest, including thepatient's lungs. As noted above, the images may be received from variousimaging devices using various imaging modalities, including a CT scan,MM scan, PET scan, X-ray scan, CBCT scan, and/or any other applicableimaging modality known to those skilled in the art. For illustrativepurposes, this description will use CT scan data as the image data.

At step S304, a 3D model of the patient's chest is generated. The 3Dmodel may be based on the image data received during step S302, imagedata previously stored on computing device 80, and/or previouslygenerated 3D models of the patient. The 3D model may show, among otherthings, the patient's lung parenchyma, such as the airways, as well asother structures such as blood vessels and lymphatic structures, amongothers.

Thereafter, at step S306, a location of anatomical features, such as thepleura of the patient's lungs as well as vascular structures and/orother physiological elements is determined, as described above. Multipleanatomical features may be identified. A determination of the locationof the pleura and vascular structures may be based on the image datareceived during step S302, and/or the 3D model generated during stepS304. For example, one or more image processing algorithms may beemployed to detect anatomical features, such as the pleura, theesophagus, the diaphragm, the heart, and/or vascular structures. In anembodiment, a region growing algorithm similar to that used duringgeneration of the 3D model may additionally or alternatively be used. Inaddition, data regarding the movement of the patient's airways duringthe patient's respiratory cycle may be used to compensate fordifferences in the detected locations of the pleural surfaces andvascular structures. Systems, devices, and methods for detectingmovement of the patient's airways during the patient's respiratory cycleare further described in commonly-owned co-pending U.S. Pat. No.10,292,619, entitled “PATIENT BREATHING MODELING”, filed on Jul. 9,2008, by Dorian Averbuch, and commonly-owned U.S. Pat. No. 7,233,820,entitled “ENDOSCOPE STRUCTURES AND TECHNIQUES FOR NAVIGATING TO A TARGETIN BRANCHED STRUCTURE”, filed on Apr. 16, 2003, by Pinhas Gilboa, theentire contents of both of which are incorporated herein by reference.

At step S308, a target location is identified in the 3D model of thepatient's airways. The target location may be the site where primarytreatment will be performed. For example, the target location may be thesite where a tumor or lesion is located. Alternatively, the targetlocation may be a previous treatment site that requires additionaltreatment. The target location may be manually selected by a clinician,and/or may be automatically determined by computing device 80 and/orapplication 81 and reviewed by the clinician.

Depending on the type of procedure being performed, additional planningsteps may be performed. For example, in a microwave ablation treatmentprocedure, the optional steps shown in box 350 of FIG. 3A may beperformed. Thus, if the procedure being performed is a microwaveablation treatment procedure, the method proceeds to step S310 afterstep S308 is completed. However, if the procedure being performed is nota microwave ablation treatment procedure, the method proceeds directlyto step S318, skipping steps S310-S316.

At step S310, ablation settings may be received by application 81. Theablation settings may include a power, temperature, and duration of theablation. The ablation settings may be entered manually by theclinician, and/or may be automatically determined by computing device 80and/or application 81 and reviewed by the clinician. Then, at step S312,application 81 may determine a projected ablation zone based on targetlocation the ablation settings. The projected ablation zone may be aspherically shaped area centered on a point at the target location towhich microwave ablation tool 104 may be navigated.

Next, at step S314, it is determined whether the projected ablation zoneencroaches on the locations of the anatomical features, e.g., the pleuraand vascular structures determined at step S306. In addition to actualencroachment, it may also be determined whether the projected ablationzone is close enough to the locations of the pleura and vascularstructures for there to be a risk of injury. If it is determined thatthe projected ablation zone encroaches on the locations of the pleuraand vascular structures, an alert may be provided at step S316. Thealert may be in the form of a visual alert displayed on computing device80, and/or an audible alert emitted by computing device 80. Application81 may further identify and/or highlight portions of the pleura and/orvascular structures which may be affected by the proposed ablation zone.

As indicated in FIG. 3A, the planning phase of the surgical procedure(e.g., steps S302-S316) are executed at least once prior to the start ofthe navigation phase, in an embodiment. In another embodiment, the stepsS302-S316 may be repeated during the navigation phase of the surgicalprocedure. Numerous other steps may performed during the planning phase,omitted here for purposes of brevity, but described in U.S. Pat. Nos.9,459,770, 9,925,009, and 9,639,666, filed by Baker et al., describedabove.

After completion of the planning phase of the surgical procedure, theclinician may initiate the navigation phase. In the embodiment describedbelow, an endobronchial EMN procedure is used for illustrative purposesto describe the various steps that may be performed. However, as will beappreciated by those skilled in the art, the same or similar steps maybe performed using a percutaneous surgical system, such as system 500 ofFIG. 5 (described below), without departing from the scope of thepresent disclosure.

Thus, in the illustrative embodiment, the navigation phase generallybegins with the insertion of bronchoscope 50, EWC 96, and EM sensor 94into the patient's airways. As noted above, EM sensor 94 may be includedin LG 92, biopsy tool 102, and/or microwave ablation tool 104. EM sensor94 may also be included in a surgical needle or other thoracoscopicinstrument or tool. In some embodiments, EM sensor 94 may be included ina surgical tool or implement that is inserted into the patient's airwayswithout the use of bronchoscope 50 and/or EWC 96.

With reference to FIG. 3B, thereafter, at step S318 of FIG. 3B, aposition of EM sensor 94 inside the patient's chest, e.g., the patient'sairways, is detected, by using, for example, EM tracking system 70. StepS318 may be iteratively repeated while EM sensor 94 is navigated aboutthe patient's airways. In some embodiments, EM sensor 94 may not belocated inside an airway but rather at some other position inside thepatient's chest, such as other lung tissue, or a tumor. In embodimentswhere multiple tools are used concurrently, EM tracking system 70 maydetect and track the positions of multiple EM sensors 94 at the sametime. Similarly, in an embodiment, an EM sensor 94 may be navigated tothe target location to mark the target location, and the marked targetlocation may then be used as a point of reference and to update theregistration. Further, the position of the target location within the 3Dmodel may be updated based on, and to correspond with, the marked targetlocation. For example, after EM sensor 94 is navigated to the targetlocation, placement of EM sensor 94 at the target location may beconfirmed using one or more imaging modalities, including a CT scan, aCBCT scan, an ultrasound scan, and/or fluoroscopy. After confirming theposition of EM sensor 94 at the target location, the position of EMsensor 94 may be marked as the target location in the 3D model. That is,the previously marked target location in the 3D model may be updated tocorrespond with the marked target location. If desired the registrationof the 3D model to the patient's airways may be updated. Regardless,having now confirmed the position of the target location and updated the3D model accordingly, even if EM sensor 94 is moved away from the targetlocation the position of EM sensor 94 can then be tracked relative tothe updated target location in the 3D model. Thereafter, the view of the3D model may be changed, such as by re-centering, based on the updatedtarget location when EM sensor 94 again approaches the target locationin the patient's body. After updating the position of the targetlocation, further tracking of EM sensor 94 may be performed based on themarked position of the target location. For example, after the targetlocation is marked, EM sensor 94 may then be tracked purely based on EMsensor 94's position in 3D space relative to the marked target location,as tracked by EM tracking system 70. That is, EM sensor 94 may benavigated to the target location, and placement of EM sensor 94 at thetarget location may be confirmed, by only using EM tracking system 70.Likewise, treatment procedures at the target location may be performedby only using EM tracking system 70 and the relevant treatment tool.

At step S320, a determination is made whether additional image data hasbeen received. For example, during the navigation phase, computingdevice 80 may receive additional image data of the patient's lungs, forexample, from a CBCT scan and/or ultrasound scan performed concurrentlywith, or at intervals during the navigation phase of the EMN procedure.Additionally or alternatively, data may be collected during thenavigation phase, such as data relating to the position of EM sensor 94.If additional image data has been received, processing proceeds to stepS322 where the 3D model is updated according to the additional data andthen to step S324. If not, processing proceeds to step S324.

At step S324, a distance between the position of EM sensor 94 (detectedat step S318) and the location of the anatomical features, e.g., thepleura and vascular structures (determined at step S306) is determined.Likewise, a direction between the position of EM sensor 94 and thelocation of the pleura and vascular structures is determined. Thisprocess may be repeated for each EM sensor 94 tracked by EM trackingsystem 70 and each anatomical feature for which a location is determinedat step S306. For example, the distance and direction between multipleEM sensors 94 may be determined. Similarly, the distance and directionbetween EM sensor 94 and multiple anatomical features may be determined.In an embodiment where EM sensor 94 is being navigated towards theanatomical feature, such as the pleura, a distance and direction to thepleura may be determined. In another embodiment where EM sensor 94 isbeing navigated away from the anatomical feature, such as the pleura,the distance and direction from the pleura may be determined. In yetanother embodiment where EM sensor 94 is between the visceral andparietal pleura, the distance and direction to one pleural surface, suchas the visceral pleura, and the distance and direction from anotherpleural surface, such as the parietal pleura, may be determined.

Thereafter, at step S326, an indication of the proximity of EM sensor 94to the location of the anatomical features, e.g., the pleura andvascular structures, is displayed. For example, a graphical userinterface (GUI), an example of which is shown in FIG. 4 (describedbelow), may be displayed by display 206 of computing device 80.Alternatively, in an embodiment where a percutaneous surgical system,such as system 500 of FIG. 5 (described below) is used, a GUI such asshown in FIG. 6 (described below) may be displayed. The indication maybe provided as the distance from the closest pleural surface or vascularstructure, and/or may include a direction indicator to the closestpleural surface or vascular structure, based on the determination atstep S324. For example, the display may include an arrow pointing in thedirection of the closest pleural surface or vascular structure, and havea distance metric, such as the distance in millimeters, to the closestpleural surface or vascular structure. The indication of the proximityof EM sensor 94 to the location of the pleura or vascular structure,including the distance and direction to the closest pleural surfaceand/or vascular structure may be iteratively updated as EM sensor 94 ismoved and new distances and directions are determined. Similarly, acount-down indicator may be displayed, representing the distance betweenEM sensor 94 and the closest pleural surface and/or vascular structure.Additionally, the indication may be in the form of an audible or sensoryindicator.

Next, at step S328, it is determined whether the entire procedure hasbeen completed. For example, application 81 may determine, based on userinput and/or based on automatic processing such as by analyzing theplanned procedure settings and the position of the tool, whether theentire procedure has been completed. If it is determined that the entireprocedure is complete, the method ends. However, if it is determinedthat the entire procedure has not been completed, the method proceeds tostep S330.

Turning now to FIG. 3C, at step S330, a determination is made as towhether EM sensor 94 is in close proximity, such as, within apredetermined distance, to an anatomical feature, e.g., a pleuralsurface and/or vascular structure. If it is determined that EM sensor 94is in close proximity to a pleural surface and/or vascular structure, aproximity alert is provided at step S332, whereafter processing returnsto step S318. The proximity alert may be a visual alert displayed byapplication 81 and/or an audible or sensory alert provided byapplication 81.

In an embodiment, data regarding the patient's respiratory cycle may beused to compensate for the movement of the patient's airways during thevarious phases of the patient's respiratory cycle. For example, before,after, or concurrently with step S330, an optional step S334, may beperformed where a determination may be made that the patient'srespiratory cycle is in a particular phase, e.g., a phase different fromthe phase during which the image data used to generate the 3D model wascollected. In such case, at step S336, an alert may be presented to theclinician that the currently displayed location of EM sensor 94 may beinaccurate, whereafter processing returns to step S318. Thenotification, which may be a displayed or audible message or signal, mayalso suggest that the clinician not navigate further for a predeterminedtime until the patient's respiratory cycle is in a different phaseduring which the location of EM sensor 94 may be accurately displayed.

Similarly, in an embodiment in which a microwave ablation tool is used,before, after, or concurrently with step S330, an optional step S338 maybe performed where application 81 determines whether the actual ablationzone is approaching the anatomical features, e.g., the pleura and/orvascular structures, or a predetermined boundary-distance therefrom. Forexample, application 81 may, based on the ablation settings received atstep S310 and a start time of the ablation procedure, determine whetherthe area of tissue actually being treated by microwave ablation tool 104is approaching a predetermined boundary-distance from the locations ofthe pleura and/or vascular structures.

If it is determined that the actual ablation zone is approaching thepredetermined boundary-distance from the locations of the pleura and/orvascular structures, an alert may be provided at step S340. Theproximity alert may be a visual alert displayed by application 81 and/oran audible or sensory alert provided by application 81. However, if itis determined that the actual ablation zone is not approaching thepredetermined boundary-distance from the locations of the pleura and/orvascular structures, the method proceeds to step S342 where it isdetermined whether the ablation phase of the procedure has beencompleted. If the ablation phase of the procedure has not beencompleted, the method returns to step S330. If the ablation phase of theprocedure is complete, the method proceeds to step S318.

Similar to the above description of the planning phase, numerous stepsof the navigation phase are omitted here for purposes of brevity, butare described in U.S. Patent Publication No. 2016/0000302, by Brown etal., described above.

Turning now to FIG. 4 , there is shown an exemplary GUI 400 forproviding proximity awareness to critical structures, according to anembodiment of the present disclosure. GUI 400 may include a view of 3Dmodel 408, showing the location of digital marker 406 representing EMsensor 94 being navigated toward a target 415. A trajectory 404 may showthe trajectory of EM sensor 94. Additionally, a proximity indicator 410(shown as a dashed line) may indicate the direction to the nearestpleural surface 402, and a measure 412 of the distance between digitalmarker 406 and pleural surface 402 may be provided. As noted above,proximity awareness may also be provided to structures other than thepleura. Thus, in such embodiments, proximity indicator 410 and measure412 may relate to such other structures.

While the above-provided embodiments are directed to providing proximityawareness to pleural surfaces and/or vascular structures, it isenvisioned that the above-described system may be used to provideguidance while navigating to a pleural surface or vascular structure,for example, to inject a dye or place a marker subpleurally or proximatethe pleural surface or vascular structure. Additionally, once such dyesor markers are placed, the system may be updated to provide proximityawareness to such dyes or markers similar to the above-described methodsof providing proximity awareness to critical structures.

While the above-described systems, devices, and methods are directed toperforming an EMN procedure, it will be appreciated by those skilled inthe art that the same or similar devices, systems, and methods may beused to perform a percutaneous surgical procedure. For example, inplanning a percutaneous surgical procedure, the clinician may take intoaccount the locations of the pleura and vascular structures whendeciding on which access route to use to a particular treatmentlocation. FIG. 5 illustrates an exemplary treatment system 500 that maybe used to perform such a percutaneous surgical procedure.

System 500 of FIG. 5 includes a computing device 80, a display 510, atable 520, a treatment tool 530, and an ultrasound sensor 540 connectedto an ultrasound workstation 550. Similar to the computing devicedescribed above with reference to FIG. 1 , computing device 80 may be,for example, a laptop computer, desktop computer, tablet computer, orother similar device. Computing device 80 may be configured to controlan electrosurgical generator, a peristaltic pump, a power supply, and/orany other accessories and peripheral devices relating to, or formingpart of, system 500. Display 510 is configured to output instructions,images, and messages relating to the performance of the treatmentprocedure. Table 520 may be, for example, an operating table or othertable suitable for use during a treatment procedure, which includes anelectromagnetic (EM) field generator 521. EM field generator 521 is usedto generate an EM field during the treatment procedure and forms part ofan EM tracking system that is used to track the positions of surgicalinstruments within the body of a patient. EM field generator 521 mayinclude various components, such as a specially designed pad to beplaced under, or integrated into, an operating table or patient bed. Anexample of such an EM tracking system is the AURORA™ system sold byNorthern Digital Inc. Treatment tool 530 is a surgical instrument forpercutaneously accessing and treating a target location. For example,treatment tool 530 may be an ablation probe having a microwave ablationantenna that is used to ablate tissue. While the present disclosuredescribes the use of system 500 in a surgical environment, it is alsoenvisioned that some or all of the components of system 500 may be usedin alternative settings, for example, an imaging laboratory and/or anoffice setting.

In addition to the EM tracking system, the surgical instruments may alsobe visualized by using ultrasound imaging. Ultrasound sensor 540, suchas an ultrasound wand, may be used to image the patient's body duringthe treatment procedure to visualize the location of the surgicalinstruments, such as treatment tool 530, inside the patient's body.Ultrasound sensor 540 may have an EM tracking sensor embedded within orattached to the ultrasound wand, for example, a clip-on sensor or asticker sensor. As described further below, ultrasound sensor 540 may bepositioned in relation to treatment tool 530 such that treatment tool530 is at an angle to the ultrasound image plane, thereby enabling theclinician to visualize the spatial relationship of treatment tool 530with the ultrasound image plane and with objects being imaged. Further,the EM tracking system may also track the location of ultrasound sensor540. In some embodiments, one or more ultrasound sensors 540 may beplaced inside the body of the patient. EM tracking system may then trackthe location of such ultrasound sensors 540 and treatment tool 530inside the body of the patient. Ultrasound workstation 550 may be usedto configure, operate, and view images captured by ultrasound sensor540.

Various other surgical instruments or surgical tools, such as LigaSure™devices, surgical staples, etc., may also be used during the performanceof a treatment procedure. In embodiment where treatment tool 530 is anablation probe, the ablation probe is used to ablate a lesion or tumor(hereinafter referred to as a “target”) by using electromagneticradiation or microwave energy to heat tissue in order to denature orkill cancerous cells. The construction and use of a system includingsuch an ablation probe is more fully described in U.S. Pat. No.10,624,697, entitled MICROWAVE ABLATION SYSTEM, filed on Aug. 26, 2014,by Dickhans, U.S. Pat. No. 9,247,992 by Latkow et al., described above,and U.S. Pat. No. 9,119,650, entitled MICROWAVE ENERGY-DELIVERY DEVICEAND SYSTEM, filed on Mar. 15, 2013, by Brannan et al., the contents ofall of which is hereby incorporated by reference in its entirety.

The location of treatment tool 530 within the body of the patient may betracked during the treatment procedure. An example method of trackingthe location of treatment tool 530 is by using the EM tracking system,which tracks the location of treatment tool 530 by tracking sensorsattached to or incorporated in treatment tool 530. Various types ofsensors may be used, such as a printed sensor, the construction and useof which is more fully described in co-pending US Patent Publication No.2016/0174873, filed Oct. 22, 2015, by Greenburg et al., the entirecontents of which is incorporated herein by reference. A percutaneoustreatment system similar to the above-described system 500 is furtherdescribed in co-pending US Patent Publication Nos. 2016/0317224,2016/0317230, 2016/0317231, 2016/0317225, and 2016/0317229, all filed onApr. 15, 2016, by Girotto et al., the entire contents of each of whichis incorporated herein by reference.

FIG. 6 shows an exemplary GUI 600 for providing proximity awareness tocritical structures, according to an embodiment of the presentdisclosure. GUI 600 may include multiple views of the 3D model of thepatient's chest. For example, coronal, sagittal, and/or axial views maybe displayed. Each view may include a representation of the patient'slungs 625. In addition, one or more of the views of GUI 600 may includea representation of the target 615 and a projected ablation zone 610.GUI 600 may further include a distance indicator 620 and arepresentation of a surgical tool 605. As noted above, application 81may display indicators 612 of a distance between surgical tool 605 andtarget 615, and/or a distance between surgical tool 605 and the closestcritical structure.

Detailed embodiments of devices, systems incorporating such devices, andmethods using the same as described herein. However, these detailedembodiments are merely examples of the disclosure, which may be embodiedin various forms. Therefore, specific structural and functional detailsdisclosed herein are not to be interpreted as limiting, but merely as abasis for the claims and as a representative basis for allowing oneskilled in the art to variously employ the present disclosure inappropriately detailed structure. While the preceding embodiments aredescribed in terms of bronchoscopy of a patient's airways, those skilledin the art will realize that the same or similar devices, systems, andmethods may be used in other lumen networks, such as, for example, thevascular, lymphatic, and/or gastrointestinal networks as well.Additionally, the same or similar methods as those described herein maybe applied to navigating in other parts of the body, such as the chestareas outside of the lungs, the abdomen, pelvis, joint space, brain,spine, etc., to identify critical structures and provide proximityawareness to critical structures in such other parts of the body.

With respect to memory 202 described above in connection with FIG. 2 ,the memory 202 may include any non-transitory computer-readable storagemedia for storing data and/or software that is executable by processor204 and which controls the operation of computing device 80. In anembodiment, memory 202 may include one or more solid-state storagedevices such as flash memory chips. Alternatively or in addition to theone or more solid-state storage devices, memory 202 may include one ormore mass storage devices connected to the processor 204 through a massstorage controller (not shown) and a communications bus (not shown).Although the description of computer-readable media contained hereinrefers to a solid-state storage, it should be appreciated by thoseskilled in the art that computer-readable storage media can be anyavailable media that can be accessed by the processor 204. That is,computer readable storage media includes non-transitory, volatile andnon-volatile, removable and non-removable media implemented in anymethod or technology for storage of information such ascomputer-readable instructions, data structures, program modules orother data. For example, computer-readable storage media includes RAM,ROM, EPROM, EEPROM, flash memory or other solid state memory technology,CD-ROM, DVD, Blu-Ray or other optical storage, magnetic cassettes,magnetic tape, magnetic disk storage or other magnetic storage devices,or any other medium which can be used to store the desired informationand which can be accessed by computing device 80.

Network interface 208 may be configured to connect to a network such asa local area network (LAN) consisting of a wired network and/or awireless network, a wide area network (WAN), a wireless mobile network,a Bluetooth network, and/or the internet. Input device 210 may be anydevice by means of which a user may interact with computing device 80,such as, for example, a mouse, keyboard, foot pedal, touch screen,and/or voice interface. Output module 212 may include any connectivityport or bus, such as, for example, parallel ports, serial ports,universal serial busses (USB), or any other similar connectivity portknown to those skilled in the art.

Further aspects of image and data generation, management, andmanipulation useable in either the planning or navigation phases of anEMN procedure are more fully described in commonly-owned U.S. PatentPublication No. 2016/0000414, entitled “METHODS FOR MARKING BIOPSYLOCATION”, filed on Jun. 29, 2015, by Brown; U.S. Patent Publication No.2016/0000517, entitled “INTELLIGENT DISPLAY”, filed on Jun. 29, 2015, byKehat et al.; U.S. Pat. No. 9,727,986, entitled “UNIFIED COORDINATESYSTEM FOR MULTIPLE CT SCANS OF PATIENT LUNGS”, filed on Jul. 1, 2015,by Greenburg; U.S. Pat. No. 10,159,447, entitled “ALIGNMENT CT”, filedon Jul. 2, 2015, by Klein et al.; U.S. Pat. No. 9,633,431, entitled“FLUOROSCOPIC POSE ESTIMATION”, filed on May 29, 2015, by Merlet; U.S.Pat. No. 9,836,848, entitled “SYSTEM AND METHOD FOR SEGMENTATION OFLUNG”, filed on Jun. 30, 2015, by Markov et al.; and U.S. PatentPublication No. 2016/0000520, entitled “SYSTEM AND METHOD OF PROVIDINGDISTANCE AND ORIENTATION FEEDBACK WHILE NAVIGATING IN 3D”, filed on Jul.2, 2015, by Lachmanovich et al., the contents of each of which arehereby incorporated by reference.

While several embodiments of the disclosure have been shown in thedrawings, it is not intended that the disclosure be limited thereto, asit is intended that the disclosure be as broad in scope as the art willallow and that the specification be read likewise. Therefore, the abovedescription should not be construed as limiting, but merely asexemplifications of particular embodiments. Those skilled in the artwill envision other modifications within the scope and spirit of theclaims appended hereto.

What is claimed is:
 1. A method for providing proximity awareness to ananatomical feature while navigating inside a patient's chest, the methodcomprising: determining a location of the anatomical feature based on atleast one of received image data of the patient's chest or a 3D model ofthe patient's chest; tracking a position of a microwave ablation deviceconfigured to deliver energy to tissue to create a growing ablationzone; indicating a proximity of the microwave ablation device relativeto the anatomical feature, based on the tracked position of themicrowave ablation device inside the patient's chest; tracking aposition of a tool; indicating a proximity of the tool relative to theanatomical feature and a proximity of the tool relative to the microwaveablation device; and determining whether a boundary of the growingablation zone created by the microwave ablation device is approachingthe anatomical feature by determining whether the boundary of thegrowing ablation zone is approaching a predetermined distance from theanatomical feature.
 2. The method of claim 1, further comprising:determining whether the microwave ablation device is within apredetermined distance from the anatomical feature; and providing aproximity alert, in response to a determination that the microwaveablation device is within the predetermined distance from the anatomicalfeature.
 3. The method of claim 2, further comprising receiving datacorresponding to movement of the patient's chest based on the patient'srespiratory cycle, and wherein determining whether the microwaveablation device is within the predetermined distance from the anatomicalfeature includes determining whether the microwave ablation device iswithin the predetermined distance from the anatomical feature based onthe data corresponding to movement of the patient's chest.
 4. The methodof claim 1, further comprising receiving data corresponding to movementof the patient's chest based on the patient's respiratory cycle, andwherein determining the location of the anatomical feature includesdetermining the location of the anatomical feature based on the datacorresponding to the movement of the patient's chest.
 5. The method ofclaim 1, further comprising: receiving image data of the patient'schest; and generating the 3D model based on the received image data. 6.The method of claim 1, wherein indicating the proximity of the microwaveablation device relative to the anatomical feature includes displaying avalue corresponding to a distance between the microwave ablation deviceand the anatomical feature, or an icon corresponding to a direction ofthe microwave ablation device relative to the anatomical feature.
 7. Themethod of claim 1, further comprising providing an alert when adetermination is made that the ablation zone created by the microwaveablation device is approaching the anatomical feature.
 8. A system forproviding proximity awareness to an anatomical feature while navigatinginside a patient's chest, the system comprising: a microwave ablationdevice configured to be inserted into the patient's chest and to createa growing ablation zone; and a computing device including a processorand a memory storing instructions which, when executed by the processor,cause the computing device to: determine a location of the anatomicalfeature based on at least one of received image data of the patient'schest or a 3D model of the patient's chest; track a position of themicrowave ablation device inside the patient's chest; indicate aproximity of the microwave ablation device relative to the anatomicalfeature, based on the tracked position of the microwave ablation deviceinside the patient's chest; and determine whether a boundary of thegrowing ablation zone created by the microwave ablation device isapproaching the anatomical feature by determining whether the boundaryof the growing ablation zone is approaching a predetermined distancefrom the anatomical feature.
 9. The system of claim 8, wherein theinstructions further cause the computing device to: determine whetherthe microwave ablation device is within a predetermined distance fromthe anatomical feature; and provide a proximity alert when adetermination is made that the microwave ablation device is within thepredetermined distance from the anatomical feature.
 10. The system ofclaim 9, wherein the instructions further cause the computing device toreceive data corresponding to movement of the patient's chest based onthe patient's respiratory cycle, and wherein the computing devicedetermines whether the microwave ablation device is within thepredetermined distance from the anatomical feature by determiningwhether the microwave ablation device is within the predetermineddistance from the anatomical feature based on the data corresponding tomovement of the patient's chest.
 11. The system of claim 8, wherein theinstructions further cause the computing device to receive datacorresponding to movement of the patient's chest based on the patient'srespiratory cycle, and wherein the computing device determines thelocation of the anatomical feature by determining the location of theanatomical feature based on the data corresponding to the movement ofthe patient's chest.
 12. The system of claim 8, wherein the instructionsfurther cause the computing device to: receive image data of thepatient's chest; and generate the 3D model based on the received imagedata.
 13. The system of claim 8, wherein the indication of the proximityof the microwave ablation device relative to the anatomical featureincludes a value corresponding to a distance between the microwaveablation device and the anatomical feature, or an icon corresponding toa direction of the microwave ablation device relative to the anatomicalfeature.
 14. The system of claim 8, wherein the instructions furthercause the computing device to: provide an alert when a determination ismade that the ablation zone created by the microwave ablation device isapproaching the anatomical feature.
 15. The system of claim 8, whereinthe instructions further cause the computing device to: track a positionof a tool; and indicate a proximity of the tool relative to themicrowave ablation device and a proximity of the tool relative to theanatomical feature.
 16. A non-transitory computer-readable storagemedium storing instructions which, when executed by a processor, cause acomputer to: receive image data or a 3D model of a patient's chest;determine a location of an anatomical feature based on at least one ofthe received image data or the generated 3D model; track a position of amicrowave ablation device and a position of a tool inside the patient'schest, wherein the microwave ablation device is configured to deliverenergy to tissue to create a growing ablation zone; indicate a proximityof the microwave ablation device relative to the anatomical feature,based on the tracked position of the microwave ablation device insidethe patient's chest; indicate a proximity of the microwave ablationdevice relative to the tool or a proximity of the tool relative to theanatomical feature; and determine whether a boundary of the growingablation zone created by the microwave ablation device is approachingthe anatomical feature by determining whether the boundary of thegrowing ablation zone is approaching a predetermined distance from theanatomical feature.
 17. The non-transitory computer-readable storagemedium according to claim 16, wherein the instructions further cause thecomputer to: determine whether the microwave ablation device is within apredetermined distance from the anatomical feature; and provide aproximity alert when a determination is made that the microwave ablationdevice is within the predetermined distance from the anatomical feature.18. The non-transitory computer-readable storage medium according toclaim 16, wherein the indication of the proximity of the microwaveablation device relative to the anatomical feature includes a valuecorresponding to a distance between the microwave ablation device andthe anatomical feature, or an icon corresponding to a direction of themicrowave ablation device relative to the anatomical feature.
 19. Thenon-transitory computer-readable storage medium according to claim 16,wherein the instructions further cause the computer to: provide an alertwhen a determination is made that the ablation zone created by themicrowave ablation device is approaching the anatomical feature.
 20. Thenon-transitory computer-readable storage medium according to claim 16,wherein the instructions further cause the computer toelectromagnetically track the position of at least one of the microwaveablation device and the tool inside a patient's chest.